INI is mostly used for save-load systems for your games. For example if you unlock an item, you can write a value or string in the INI and then save that .ini file. You can then load the file up the next time someone plays your game and retrieve that data.
If your just talking about unlocks in your game across multiple frames, you can use the global strings and values to communicate data between the frames. For example, at the end of the frame set global string A to "unlocked". Then at the next frame when you test Global String A = "unlocked" you do an action.